1 стрOmphalocele is a rare abdominal wall defect in which the intestines, liver, and occasionally other organs remain outside of the abdomen in a sac because of failure of normal return of intestines and other contents back to abdominal cavity during around ninth week of intrauterine development.
2стр The Centers for Disease Control and Prevention (CDC) estimates that each year about 775(seven hundred and seventy five) babies in the United States are born with an omphalocele. In other words, about 1 out of every 5386 (Five thousand three hundred eighty six )babies born in the United States each year is born with an omphalocele. Many babies born with an omphalocele also have other birth defects, such as heart defects, neural tube defects, and chromosomal abnormalities.
The causes of omphalocele among most infants are unknown. Some babies have omphalocele because of a change in their genes or chromosomes. Omphalocele might also be caused by a combination of genes and other factors, such as the things the mother comes in contact with in the environment or what the mother eats or drinks, or certain medicines she uses during pregnancy.
possible reasons desease:
Alcohol and tobacco: Women who consumed alcohol or were heavy smokers (more than 1 pack a day) were more likely to have a baby with omphalocele.
4 стр Certain medications: Women who used selective serotonin-reuptake inhibitors (SSRIs) during pregnancy were more likely to have a baby with an omphalocele.
5стр Obesity: Women who were obese or overweight before pregnancy were more likely to have a baby with an omphalocele6 стрTreatments
If the omphalocele is small (only some of the intestine is outside of the belly), it usually is treated with surgery soon after birth to put the intestine back into the belly and close the opening. If the omphalocele is large (many organs outside of the belly), the repair might be done in stages. 7 стр The exposed organs might be covered with a special material,8 стр and slowly, over time, the organs will be moved back into the belly. When all the organs have been put back in the belly, the opening is closed.